[Locally invasive papillary thyroid cancer--our experience].

نویسندگان

  • Drago Prgomet
  • Mario Bilić
  • Lana Kovac
  • Zdenka Hutinec
  • Iva Topić
چکیده

Differentiated thyroid carcinomas, particularly papillary carcinoma, are the tumors with good prognosis, but sometimes have a tendency to spread into the surrounding tissue. The spread of these tumors usually involves muscle, cartilage and upper aerodigestive tract. During two years (2008-2009) at the Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Center Zagreb, 233 patients with differentiated thyroid carcinoma were treated. Among them there were 23 cases of locally invasive papillary thyroid carcinoma. In this paper we present our experience in treating 23 patients with locally invasive papillary thyroid carcinoma with special reference to extrathyroid spread, surgery and postoperative treatment. Our recommendations for the treatment of such patients are total thyroidectomy and selective neck dissection, removal of macroscopically visible tumors, radical surgery for tumors with intraluminal expansion in the upper aerodigestive tract and postoperative adjuvant therapy.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Large Remnant Ablation in the Treatment of Metastatic Papillary Thyroid Carcinoma: Case Report and Literature Review

Surgery remains the mainstay for treatment of differentiated thyroid carcinoma. Total or near-total thyroidectomy followed by radioiodine (I-131) ablation of residual thyroid tissue is the recommended treatment for high-risk disease, including those patients with macroscopic tumor invasion and distant metastases [1]. However, total or near-total thyroidectomy is not always possible, especially ...

متن کامل

Invasive Tall Cell Variant of Papillary Cancer originating from the Pyramidal Lobe of the Thyroid Gland

A pyramidal lobe of the thyroid gland is a common anatomic variant. However, primary malignancy of the pyramidal lobe is rare with the exception of cancer in a thyroglossal duct cyst. A 61-year-old morbidly obese woman presented with a 30 lb. weight loss and a large asymptomatic submental neck mass that extended to the base of her tongue. The mass was invading the hyoid bone and the sternohyoid...

متن کامل

Mouse Models of Follicular and Papillary Thyroid Cancer Progression

A significant number of well-differentiated thyroid cancers progress or recur, becoming resistant to current therapeutic options. Mouse models recapitulating the genetic and histological features of advanced thyroid cancer have been an invaluable tool to dissect the mechanisms involved in the progression from indolent, well differentiated tumors to aggressive, poorly differentiated carcinomas, ...

متن کامل

Brachial plexus compression: a rare sequelae of malignant papillary thyroid carcinoma.

Invasive papillary thyroid carcinoma (PTC) can rarely invade adjacent vital structures. There has been one report on secondary brachial plexopathy associated with locally invasive PTC. Here we report a patient with a large locally invasive PTC associated with secondary neoplastic brachial plexopathy. The case exhibits an extremely rare occurrence that has substantial impact on surgical planning...

متن کامل

Incidence of thyroid papillary cancer in contralateral lobe

Background & objectives: Prognosis of thyroid papillary cancer is quite well long lasting, so a 10- year survival is observed in more than 90% cases. In this study, rate of incidence of thyroid papillary cancer in contralateral lobe was assessed among patients who had a surgical thyroidectomy re-operation. Materials & Methods: In this retrospective study, we examined 82 patients diagnosed with...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Lijecnicki vjesnik

دوره 134 9-10  شماره 

صفحات  -

تاریخ انتشار 2012